BEGINNER - If you are not familiar with skincare products containing spicules, we do not recommend using them with our AGE-R devices.
Step 1. After cleansing, prepare your skin with Meicube's Zero Pore Pads (or other hydrating toners).
Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g., areas with uneven texture, enlarged pores, etc.) and gently rub and press to aid absorption.
Step 3. Finish with Medicube's Collagen Jelly Cream (or your daily water-based moisturizer).

STANDARD - Step 1. After cleansing, apply the Zero One Day Exosome Shot to your entire face, avoiding the area near your eyes and lips. For the best results, we recommend using the Exosome Shot as the first step in your skincare routine.
Step 2. Gently rub and press with your hands to ensure that the needle-like formula is absorbed deep into your skin.
Step 3. Finish with Medicube's Collagen Jelly Cream (or your daily water-based moisturizer).

• Exosome-coated Spicule (Hydrolyzed sponge): Taking the form of needles, spicules penetrate the skin’s surface like micro-needles to refine pores and improve overall skin health—delivering deeper, more effective care than typical spicule-based products
• Lacto Exosome: Medicube’s patented Exosome is a powerhouse blend of peptides, amino acids, glutathione, and vitamins. It revitalizes damaged skin, boosts resilience, and targets daily skin concerns—promoting natural skin health with energy and visible results
• AHA + BHA + PHA: Powerhouse ingredients that aid in resurfacing textured skin, dissolving dead skin cells, and promoting skin renewal
• Niacinamide: Boosts the skin’s barrier and delivers hydration
• Panthenol: Soothes the skin and helps improve hydration levels

Water, Dipropylene Glycol, Glycerin, Butylene Glycol, 1,2-Hexanediol, Niacinamide, Sodium Polyacrylate, Ethylhexyl Palmitate, Hydrolyzed Sponge, C12-14 Alketh-12, Hydrogenated Polydecene, Ethylhexylglycerin, Adenosine, Caprylyl/Capryl Glucoside, Disodium EDTA, Panthenol, Calcium Silicate, Lactobacillus Extracellular Vesicles, Campsis Grandiflora Flower Extract, Pueraria Lobata Root Extract, Pinus Palustris Leaf Extract, Oenothera Biennis (Evening Primrose) Flower Extract, Ulmus Davidiana Root Extract, Sodium Silicate, Betaine Salicylate, Citric Acid, Gluconolactone 25000 | Water, Glycereth-26, Dipropylene Glycol, Butylene Glycol, Caprylic/Capric Triglyceride, Niacinamide, Calcium aluminum borosilicate, Hydrolyzed Sponge, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, 1,2-Hexanediol, Caprylyl Glycol, Isohexadecane, Glycerin, Polysorbate 80, Carbomer, Tromethamine, Panthenol, Ethylhexylglycerin, Adenosine, Sorbitan Oleate, Sorbitan Isostearate, Polysorbate 60, Disodium EDTA, Lactobacillus Extracellular Vesicles(154 ppm), Kummerowia Striata Extract, Oenothera Biennis (Evening Primrose) Flower Extract, Ulmus Davidiana Root Extract, Pinus Palustris Leaf Extract, Pueraria Lobata Root Extract, Cinchona Pubescens Bark Extract, Gluconolactone, Betaine Salicylate, Citric Acid, Milk Exosomes(10 ppm), Leptospermum Scoparium Leaf Extract, Hydrogenated Lecithin, Polyglyceryl-10 Laurate, Ceramide NP, Acetyl Tetrapeptide-5, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-5.